2023
Modeling and Remodeling the Cell: How Digital Twins and HCMV Can Elucidate the Complex Interactions of Viral Latency, Epigenetic Regulation, and Immune Responses. Current Clinical Microbiology Reports. DOI: 10.1007/s40588-023-00201-w
Hana McMahon-Cole, Alicia Johnson, Sara Sadat Aghamiri, Tomas Helikar, and Lindsey B. Crawford
Hematopoietic stem cells and betaherpesvirus latency. Frontiers in Cellular and Infection Microbiology. DOI: 10.3389/fcimb.2023.1189805
Lindsey B. Crawford
2022
Human Embryonic Stem Cells as a Model for Hematopoietic Stem Cell Differentiation and Viral Infection. Current Protocols. DOI: 10.1002/cpz1.622
Lindsey B. Crawford
Advances in Model Systems for Human Cytomegalovirus Latency and Reactivation. mBio. DOI: 10.1128/mbio.01724-21
Lindsey B. Crawford, Nicole L. Diggins, Patrizia Caposio, and Meaghan H. Hancock.
2021
CD34+ Hematopoietic Progenitor Cell Subsets Exhibit Differential Ability to Maintain Human Cytomegalovirus Latency and Persistence. Journal of Virology.
Lindsey B. Crawford, Meaghan H. Hancock, Hillary M. Struthers, Daniel N. Streblow, Andrew D. Yurochko, Patrizia Caposio, Felicia D. Goodrum, and Jay A. Nelson.
Human Cytomegalovirus miR-US25-1 Targets the GTPase RhoA to Inhibit CD34+ Hematopoietic Progenitor Cell Proliferation to Maintain the Latent Viral Genome. mBio.
Nicole L. Diggins, Lindsey B. Crawford, Meaghan H. Hancock, Jennifer Mitchell, and Jay A. Nelson
Human Cytomegalovirus UL7, miR-US5-1 and miR-UL112-3p Inactivation of FOXO3 Protects CD34+ Hematopoietic Progenitor Cells from Apoptosis. mSphere.
Meaghan H. Hancock, Lindsey B. Crawford, Wilma Perez, Hillary M. Struthers, Jennifer Mitchell, and Patrizia Caposio.
2020
Human Cytomegalovirus Infection Suppresses CD34+ Progenitor Cell Engraftment in Humanized Mice. Microorganisms.
Lindsey B. Crawford, Rebecca Tempel, Daniel N. Streblow, Andrew D. Yurochko, Felicia D. Goodrum, Jay A. Nelson, and Patrizia Caposio.
Human Cytomegalovirus miRNAs Regulate TGF-B to Mediate Myelosuppression while Maintaining Viral Latency in CD34+ Hematopoietic Progenitor Cells. Cell Host and Microbe.
Meaghan H. Hancock* and Lindsey B. Crawford*, Andrew H. Pham, Jennifer Mitchell, Hillary M. Struthers, Andrew D. Yurochko, Patrizia Caposio, and Jay A. Nelson
Spatial and biochemical interactions between bone marrow adipose tissue and hematopoietic stem and progenitor cells. Bone.
Jacob J. Robino, Nathalie Parmir, Sara Rosario, Lindsey B. Crawford, Benjamin J. Burwitz, Charles T. Roberts Jr, Peter Kurre, and Oleg Varlamov
for publications prior to 2020 please see Dr. Crawford's NCBI my bibliography link at the top of the page
2025
Medica S, Denton M, Diggins NL, Kramer-Hansen O, Crawford LB, Mayo AT, Perez WD, Daily MA, Parkins CJ, Slind LE, Pung LJ, Weber WC, Jaeger HK, Streblow ZJ, Sulgey G, Kreklywich CN, Alexander T, Rosenkilde MM, Caposio P, Hancock MH, Streblow DN. Third intracellular loop of HCMV US28 is necessary for signaling and viral reactivation. J Virol. 2025 Jan 31;99(1):e0180124. doi: 10.1128/jvi.01801-24. Epub 2024 Dec 10. PubMed PMID: 39655954; PubMed Central PMCID: PMC11784217.
2023
Dirck A, Diggins NL, Crawford LB, Perez WD, Parkins CJ, Struthers HH, Turner R, Pham AH, Mitchell J, Papen CR, Malouli D, Hancock MH, Caposio P. HCMV UL8 interaction with β-catenin and DVL2 regulates viral reactivation in CD34(+) hematopoietic progenitor cells. J Virol. 2023 Oct 31;97(10):e0124123. doi: 10.1128/jvi.01241-23. Epub 2023 Sep 29. PubMed PMID: 37772824; PubMed Central PMCID: PMC10617580.
Medica S, Crawford LB, Denton M, Min CK, Jones TA, Alexander T, Parkins CJ, Diggins NL, Streblow GJ, Mayo AT, Kreklywich CN, Smith P, Jeng S, McWeeney S, Hancock MH, Yurochko A, Cohen MS, Caposio P, Streblow DN. Proximity-dependent mapping of the HCMV US28 interactome identifies RhoGEF signaling as a requirement for efficient viral reactivation. PLoS Pathog. 2023 Oct;19(10):e1011682. doi: 10.1371/journal.ppat.1011682. eCollection 2023 Oct. PubMed PMID: 37782657; PubMed Central PMCID: PMC10569644.
Moy MA, Collins-McMillen D, Crawford L, Parkins C, Zeltzer S, Caviness K, Zaidi SSA, Caposio P, Goodrum F. Stabilization of the human cytomegalovirus UL136p33 reactivation determinant overcomes the requirement for UL135 for replication in hematopoietic cells. J Virol. 2023 Aug 31;97(8):e0014823. doi: 10.1128/jvi.00148-23. Epub 2023 Aug 11. PubMed PMID: 37565749; PubMed Central PMCID: PMC10506481.
for collaborative publications prior to 2023 please see Dr. Crawford's NCBI my bibliography link at the top of the page